Drug-Target Interaction
Drug-Target Interaction: Overview
This topic covers concepts such as Drug-Target Interaction, Enzymes, Receptors, Enzymes as Drug Targets, Catalytic Action of Enzymes, Drug-enzyme Interaction : Enzyme Inhibition, Receptor as Drug Targets, Enzyme Inhibitors, etc.
Important Questions on Drug-Target Interaction
What is the difference between an agonist and an antagonist?
Allosteric sites on an enzyme are:
Which of the following is not related to drug-enzyme interaction?
Arrange the sequences in enzyme action
(A) Product releases and free enzyme again binds to another substrate molecule
(B) Enzyme to alter its shape
(C) Substrate binds to active site of the enzyme
(D) Fits in to the active site
(E) Formation of enzyme product complex
The correct answer is
What is true for a competitive inhibitor?
Which type of inhibitor binds at the active site?
Which of the following statements are incorrect about receptor proteins?
Among the following which drugs mimic natural messengers ?
Incorrect statement among the follwoing is :
The enzyme which converts maltose to glucose is
The correct match between Item I and Item II is:
| Item-I | Item-II | ||
| (A) | Allosteric effect | (P) | Molecule binding to the active site of enzyme |
| (B) | Competitive inhibitor | (Q) | Molecule crucial for communication in the body |
| (C) | Receptor | (R) | Molecule binding to a site other than the active site of enzyme |
| (D) | Poison | (S) | Molecule binding to the enzyme covalently |
Correct matching is
| Column-I | Column-II | ||
| Allosteric site | These bind to a different site of enzyme | ||
| Poison | It binds to the active site | ||
| Receptor | It binds at active site by covalent bond | ||
| Competitive inhibitor | Important for communication | ||
Jacob and Monod named some enzymes as allosteric whose activity is regulated by
The site of action of insulin is
Fumerase enzyme belongs to which class
To explain the mechanism of enzymatic action, who proposed "Lock and key hypothesis''
Which of the following is not a co-enzyme
Which of the following is not an attribute of enzymes
In plants, enzymes are present
